Alzheimers Disease – A Brief Overview
References
Urbanelli L, Magini A, Ciccarone V, Trivelli F, Polidoro M, Tancini B, Emiliani C: New perspectives for the diagnosis of Alzheimer's disease. Recent patents on CNS drug discovery 2009, 4:160-181.
Blurton-Jones M, LaFerla FM: Pathways by which A facilitates tau pathology. Current Alzheimer Research 2006, 3:437-448.
Iqbal K, Grundke-Iqbal I: Ubiquitination and abnormal phosphorylation of paired helical filaments in Alzheimer's disease. Molecular neurobiology 1991, 5:399-410.
Imahori K, Hoshi M, Ishiguro K, Sato K, Takahashi M, Shiurba R, Yamaguchi H, Takashima A, Uchida T: Possible role of tau protein kinases in pathogenesis of Alzheimer’s disease. Neurobiology of aging 1998, 19:S93-S98.
Selkoe DJ: Aging, amyloid, and Alzheimer's disease: a perspective in honor of Carl Cotman. Neurochemical research 2003, 28:1705-1713.
Selkoe DJ: Alzheimer's disease beyond 1994: The path to therapeutics. Neurobiology of aging 1994, 15:131-133.
Hayden EY, Teplow DB: Amyloid β-protein oligomers and Alzheimer’s. 2013.
Braak H, Braak E: Diagnostic criteria for neuropathologic assessment of Alzheimer’s disease. Neurobiology of aging 1997, 18:S85-S88.
Braak H, Braak E: Argyrophilic grain disease: frequency of occurrence in different age categories and neuropathological diagnostic criteria. Journal of neural transmission 1998, 105:801-819.
Hardy J, Selkoe DJ: The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
Guiroy DC, Miyazaki M, Multhaup G, Fischer P, Garruto RM, Beyreuther K, Masters CL, Simms G, Gibbs CJ, Gajdusek DC: Amyloid of neurofibrillary tangles of Guamanian parkinsonism-dementia and Alzheimer disease share identical amino acid sequence. Proceedings of the National Academy of Sciences 1987, 84:2073-2077.
Hutton M, Pérez-Tur J, Hardy J: Genetics of Alzheimer’s disease. Essays Biochem 1998, 33:117-131.
Soto C: Unfolding the role of protein misfolding in neurodegenerative diseases. Nature Reviews Neuroscience 2003, 4:49-60.
Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI: Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc. Journal of Biological Chemistry 2000, 275:19439-19442.
Rijal Upadhaya A, Capetillo-Zarate E, Kosterin I, Abramowski D, Kumar S, Yamaguchi H, Walter J, Fändrich M, Staufenbiel M, Thal DR: Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice. Neurobiology of aging 2012, 33:2641-2660.
Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ, Selkoe DJ: Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo. Nature 2002, 416:535-539.
Leung E, Guo L, Bu J, Maloof M, Khoury JE, Geula C: Microglia activation mediates fibrillar amyloid-β toxicity in the aged primate cortex. Neurobiology of aging 2011, 32:387-397.
Tabner BJ, Turnbull S, El-Aganf O, Allsop D: Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. Current topics in medicinal chemistry 2001, 1:507-517.
Lahiri DK, Maloney B: Beyond the signaling effect role of amyloid-β< sub> 42 on the processing of APP, and its clinical implications. Experimental neurology 2010, 225:51-54.
Prasad KN, Hovland AR, Cole WC, Prasad KC, Nahreini P, Edwards-Prasad J, Andreatta CP: Multiple antioxidants in the prevention and treatment of Alzheimer disease: analysis of biologic rationale. Clinical neuropharmacology 2000, 23:2-13.
Hegde ML, Hegde PM, Rao K, Mitra S: Oxidative genome damage and its repair in neurodegenerative diseases: function of transition metals as a double-edged sword. Journal of Alzheimer's Disease 2011, 24:183-198.
Sultana R, Perluigi M, Allan Butterfield D: Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain. Free Radical Biology and Medicine 2013, 62:157-169.
Laurijssens B, Aujard F, Rahman A: Animal models of Alzheimer's disease and drug development. Drug Discovery Today: Technologies 2013, 10:e319-e327.
Sundaram P, Sundaram RK, Kasinathan C, Stein S: Detoxification Depot for-Amyloid Peptides. Current Alzheimer Research 2008, 5:26-32.
Mapstone M, Cheema AK, Fiandaca MS, Zhong X, Mhyre TR, MacArthur LH, Hall WJ, Fisher SG, Peterson DR, Haley JM: Plasma phospholipids identify antecedent memory impairment in older adults. Nature medicine 2014.
DOI: http://dx.doi.org/10.14259%2Fmn.v1i1.106
Refbacks
- There are currently no refbacks.