Acquired Legionnaire’s disease through aerosolization of water from natural sources

Authors

  • Roopali Mittal Miami Children Hospital, Miami, Florida 33155
  • Arun Agrawal Indiana University Health, Indianapolis, IN; 46202
  • Richard Roach Indiana University Health, Indianapolis, IN; 46202
  • Terrisha Buckley Tuskegee University image/svg+xml
  • Amit K Tiwari Tuskegee University image/svg+xml

DOI:

https://doi.org/10.14259/tcb.v1i1.61

Keywords:

Legionella, Legionnaire’s disease, Fresh water infections

Abstract

Legionnaire’s disease is a potentially fatal pneumonia caused by Legionella pneumophila bacteria. Aerosol inhalations by human-generated sources are linked to the breakout of Legionnaire's disease. This epidemiological review highlights the survival of Legionella in natural habitats and its possible role in sporadic cases of Legionnaire’s diseases. In addition, we reason other possible natural sources, which may cause Legionella epidemic. 

Author Biography

  • Amit K Tiwari, Tuskegee University
    Dr. Amit K. Tiwari received his Pharmacy degree in 2005 from R.I.V.T.E, G.Noida, India and later received his Masters and Ph.D. degree in Pharmacology from Saint John’s University, Queens, NY, USA in the year 2008 and 2011, respectively. He won numerous fellowship awards at St. John’s University including the prestigious University Fellowship in 2010. He finished his Post-Doctoral training at Mount Sinai School of Medicine, NYC, NY, USA in 2011, focusing on Pharmacokinetic/Pharmacodynamic driven anticancer drug development. Dr. Tiwari is currently a Principal Investigator and Assistant Professor in the Department of Biomedical Sciences in CVMNAH, Tuskegee University, Alabama. Dr. Tiwari research is focused in the area of experimental therapeutics to develop novel strategies to combat cancer. He has also extensively characterized the drug resistance mechanism of novel anticancer drugs and has shown ways to improve cancer chemotherapy. Dr. Tiwari long-term research objective is to understand molecular events, biomarkers and signaling pathways that contribute to disparity in cancer progression with the hope of controlling cancer in vulnerable communities. Dr. Tiwari believes that using systems biology approach with the goal of translation to the bedside can develop novel potential therapeutic approaches for the prevention of cancer. Dr. Tiwari is an Editor of VRI Cell Signaling and Journal of Life Sciences. Dr. Tiwari is on the editorial board of over 10 international and national journals including Frontiers in Pharamcology, Analytical Oncology, Journal of Experimental Sciences, Current Clinical Pharmacology etc. Dr. Tiwari serves as a reviewer of over 40 peer-reviewed journals and has extensively published in the field of drug resistance, experimental therapeutics and novel drug development. Dr. Tiwari is often invited and has presented his work at several international conferences. Dr. Tiwari has authored over 30 publications as a research articles, reviews, book chapters and editorial in high impact peer-reviewed journals. 

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Published

2013-10-03

Issue

Vol. 1 No. 1 (2013): First Issue: October, 2013

Section

Case Reports

How to Cite

Mittal, R., Agrawal, A., Roach, R., Buckley, T., & Tiwari, A. K. (2013). Acquired Legionnaire’s disease through aerosolization of water from natural sources. Translational Clinical Biology, 1(1), pp.6-9. https://doi.org/10.14259/tcb.v1i1.61

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