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Chemical and biological studies of 2-(2'- pyridyl) benzimidazole and its synthesized derivatives.

Arfa Kamil, Shamim Akhter, Maryam Ahmad, Ghazala H Rizwani, Sarwat Jahan, Sohail Hassan, Shaheena Fayyaz, Shaukat Mahmud


A series of 2-(2'-Pyridyl) benzimidazole (Ia) compound was synthesized and derivative compounds 1-11 were characterized through physical and spectral data was carried out by UV, IR, Mass and nuclear magnetic resonance spectroscopy (1H NMR). All these synthesized compounds were screened in vitro at different doses for their phytotoxicity and nematicidal activity against Rootknot nematode Meloidogyne incognita. The activities obtained were compared with the reference drugs as, Paraquat for phytotoxic and Furadan for anthelmintic activity.


Benzimidazole, Phytotoxicity, Nematicidal activity, Meloidogyne incognita

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