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Pharmaceutical Standardization and Evaluation of Herbomineral Cream (ALG-06) for Leucoderma

Ambreen Huma, Ghazala H Rizwani, Muhammed Usman, Maryam Ahmed, Shakeel Ahmed Ansari

Abstract


The aim of this study was to formulate and evaluate the herbomineral cream ALG-O6 which is used in the treatment of leucoderma. In this formulation we used mineral drugs (red oxide and purified sulphur) along with specific combination of four common medicinal herbs (i.e. Azadiracta indica A Juss. Psoralea corylifolia L., Punica granatum L., Trigonella foenum-graecum L.) in the extract form. The quality of   the cream (ALG-O6) was evaluated by organoleptic features (color, odor and appearance) and on other hand its chemical and  physical characteristics such as pH,viscosity, solubility in different solvents along with  bio burden  and irritancy test on the skin was also performed. Cream was observed in the accelerated stability condition at room temperature (RT) and 40°C/75% (RH) for a period of 6 months. Phytochemical screening of herbomineral extract (HME) and standardization were carried out by TLC finger prints of extract with two different solvent systems

Keywords


Accelerated stability, phytochemical, Leucoderma

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References


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DOI: http://dx.doi.org/10.14259%2Fpm.v1i1.14

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